Alternative HealthGrand Forks

Men's health & testosterone

What Does My Doctor Monitor Throughout My Testosterone Therapy Journey?

Testosterone treatment comes with regular follow-up. Here are the labs, check-ins, and symptoms your clinician may discuss, and why they matter.

Key takeaways
  • Monitoring is part of testosterone treatment for as long as you are on it.
  • Common checks include testosterone levels, hematocrit, and, for many men, PSA.
  • Symptoms like snoring, swelling, or mood changes are worth reporting between visits.
  • Your schedule depends on your health, your treatment, and your clinician's judgment.

If you and your clinician decide that testosterone treatment makes sense for you, the decision does not end with a prescription. Treatment comes with regular follow-up, because testosterone affects more than one part of the body. This guide explains the kinds of monitoring that may be discussed and why they matter. Your own plan will depend on your health and on Dr. Ewals's judgment.

Why Monitoring Matters

Monitoring helps answer three questions. Is the treatment doing what it is meant to do? Is it causing side effects you might not notice on your own? And is it still the right choice for you? Both the American Urological Association (AUA) and the Endocrine Society include follow-up in their guidance on testosterone treatment. Guidelines describe check-ins in the first months after starting and then at regular intervals.

Before You Start: Baseline Tests

Monitoring starts before the first dose. Baseline tests give a reference point to compare against later. According to the AUA guideline, these include:

  • Hemoglobin and hematocrit, which measure red blood cells.
  • PSA (prostate-specific antigen) for men over 40, to check for signs of prostate cancer before treatment.

Your clinician may also ask about sleep, snoring, fertility plans, heart health, and urinary symptoms before starting.

What May Be Checked During Treatment

Testosterone Levels

Follow-up blood tests show whether your level is in the intended range. When the blood is drawn can matter, depending on the form of testosterone you use, so follow your clinician's timing instructions.

Hematocrit

Testosterone can raise red blood cell counts. This is called erythrocytosis. A high hematocrit can make the blood thicker, so it is watched with regular blood tests. If it rises, the clinician may change the dose or plan.

PSA and Prostate Health

For many men, especially over 40, PSA may be rechecked during treatment, and the clinician may ask about urinary symptoms. The Endocrine Society guideline describes when a change in PSA should lead to a urology referral.

Blood Pressure and General Health

Blood pressure and overall heart health are part of routine check-ins.

Symptoms to Report Between Visits

Some changes are easier for you to notice than for a lab test. Tell the clinic if you notice:

  • New or louder snoring, gasping at night, or more daytime sleepiness. Testosterone may worsen untreated sleep apnea.
  • Swelling in your ankles or legs, which can be a sign of fluid retention.
  • New acne or oily skin.
  • Breast tenderness or swelling.
  • Changes in mood, irritability, or sleep.
  • Trouble urinating or changes in urine flow.
  • Skin irritation where you apply a gel or patch.

If you have chest pain, trouble breathing, weakness on one side, or sudden leg swelling with pain, get emergency care right away.

If you use a testosterone gel, ask about how to avoid passing it to others through skin contact, especially children and women. FDA labeling for gels includes a warning about this.

Fertility

Testosterone treatment can lower sperm production. If you might want children now or in the future, bring it up before starting and at follow-up visits. Your clinician can talk with you about options, which may include other medicines or a referral.

Stopping or Changing Treatment

Don't stop or change your dose on your own. If you want to stop, talk with your clinician about what to expect and how your body's own production may respond. Monitoring may continue for a while after stopping.

Next Steps

If you are wondering whether testosterone is even the right question, start with what a low testosterone evaluation can and cannot tell you. To talk through your own situation, see our testosterone consultation page or book a visit.

Sources

  1. American Urological Association: Testosterone Deficiency Guideline
  2. Endocrine Society: Testosterone Therapy in Men with Hypogonadism guideline
  3. FDA: Testosterone Information
  4. MedlinePlus: Testosterone Levels Test

Questions

Related Questions

Short answers on the same topic as this guide. Still unsure? Call Will at (218) 274-4500.

See every question
How much does TRT cost at Alternative Health?
  • Initial consultation: $190. If you qualify and decide to start treatment, it includes your first month of testosterone, supplies and shipping.
  • After that: $190/month, OR
  • Pay $2,000 upfront for the whole year and save $280. ($190 consultation fee is credited toward membership, leaving a balance of $1,810)
  • Follow-up visits are included in both plans.
  • Lab work is billed separately by the lab you choose. (If you don't have a preference, we can refer you to a lab.)

Request a Consultation

Do I need lab work before a testosterone consultation?

Usually, yes. Call us for a lab order, complete the labs, and then book your visit so Dr. Ewals can review the results with you. Low testosterone is generally confirmed with early-morning blood tests on more than one day, not symptoms alone.

What are the top 10 symptoms of low testosterone?

The most common symptoms of low testosterone (low T) are:

  1. Reduced sex drive (low libido)
  2. Difficulty getting or keeping an erection, including fewer morning erections
  3. Persistent fatigue and low energy
  4. Loss of muscle mass and strength
  5. More body fat, especially around the midsection
  6. Depressed mood or irritability
  7. Difficulty concentrating, forgetfulness or brain fog
  8. Poor sleep
  9. Reduced facial or body hair
  10. Enlarged or tender breast tissue

Every one of these has other possible causes, including sleep apnea, thyroid problems, medicines and stress. Low testosterone is confirmed with early-morning blood tests, not symptoms alone, which is why we test rather than guess.

How Is Low Testosterone Diagnosed According to Medical Guidelines?

Alternative Health's approach to evaluating low testosterone is informed by established medical guidelines from the Endocrine Society, American Urological Association (AUA), and European Association of Urology (EAU).

A diagnosis of testosterone deficiency generally requires:

  • Symptoms or signs consistent with low testosterone.
  • Low testosterone confirmed by two separate early-morning blood tests.
  • Medical evaluation to identify possible underlying causes.
  • Individualized assessment of treatment benefits, risks, and monitoring requirements.

Sexual symptoms, including reduced libido, fewer morning erections, and erectile dysfunction, are more specifically associated with testosterone deficiency than fatigue, low motivation, or mood changes alone.

Symptoms do not confirm a diagnosis. Testosterone replacement therapy (TRT) should be considered only after appropriate laboratory testing and clinical evaluation.

Clinical References:

What are the most common types of TRT?

Testosterone replacement therapy comes in five main forms. Injections and gels are the most commonly prescribed.

  • Injections: testosterone cypionate, enanthate, Xyosted or long-acting Aveed.
  • Gels: applied to the skin once a day, such as AndroGel.
  • Oral capsules: Jatenzo, Tlando or Kyzatrex, usually twice a day.
  • Pellets: implanted under the skin, lasting about three to six months.
  • Nasal gel: Natesto, used three times a day.

The right option depends on your labs, health history and fertility plans. Compare all five types.

How Do Doctors Diagnose Low Testosterone According to Medical Guidelines?

According to the Endocrine Society and American Urological Association (AUA), diagnosing low testosterone (male hypogonadism) requires compatible symptoms, low testosterone confirmed by two separate early-morning blood tests, and a medical evaluation to identify potential underlying causes.

What does treatment involve if my levels are low?

Dr. Ewals sets a dose and shows you how the medicine is taken. Your medication and home-use supplies are shipped to you as part of the TRT membership. Follow-up visits are every 8 to 24 weeks, depending on the person, and your dose is adjusted from your lab results.

How often will I need labs on treatment?

Once your levels are stable, usually after 2 to 4 months, labs are typically every 3 to 6 months. They check testosterone, red blood cell count and other markers. Labs are billed by the lab and aren't included in the TRT membership.

What is PSA, and how does testosterone therapy affect it?

PSA (prostate-specific antigen) is a protein made by the prostate. A blood test measures it, and a higher level can point to a prostate problem, such as an enlarged or inflamed prostate or, less often, prostate cancer.

Testosterone therapy can raise PSA slightly, usually in the first months of treatment. That's why the guidelines call for:

  • A PSA test before starting for men over 40 (American Urological Association).
  • A repeat test 3 to 12 months after starting, then on a regular schedule.
  • A urology referral if PSA rises by more than 1.4 ng/mL in the first year, or is confirmed above 4.0 ng/mL (Endocrine Society).

Men with prostate cancer, or who are being evaluated for it, should not start testosterone. PSA is part of the labs reviewed before and during treatment.

What did the FDA change about testosterone in 2025?

Two things. After a large trial (TRAVERSE) found no increase in major heart problems, the FDA had testosterone labels updated to reflect those results. It also required a warning that testosterone can raise blood pressure, so Dr. Ewals monitors yours.

Who shouldn't take testosterone?

Men with or being evaluated for prostate or breast cancer, untreated severe sleep apnea, uncontrolled heart failure or a very high red blood cell count, and men trying to conceive now. Dr. Ewals goes through all of this before anything is prescribed.

Can testosterone treatment affect fertility?

Yes. Testosterone therapy can lower sperm production. If you might want children, say so at your first visit so you can discuss other options.

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